Hyperspectral imaging benchmark based on machine learning for intraoperative brain tumour detection

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Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment

Histone H4 acetylation at Lysine 16 (H4K16ac) is a key epigenetic mark involved in gene regulation, DNA repair and chromatin remodeling, and though it is known to be essential for embryonic development, its role during adult life is still poorly understood. Here we show that this lysine is massively hyperacetylated in peripheral neutrophils. Genome-wide mapping of H4K16ac in terminally differentiated blood cells, along with functional experiments, supported a role for this histone post-translational modification in the regulation of cell differentiation and apoptosis in the hematopoietic system. Furthermore, in neutrophils, H4K16ac was enriched at specific DNA repeats. These DNA regions presented an accessible chromatin conformation and were associated with the cleavage sites that generate the 50 kb DNA fragments during the first stages of programmed cell death. Our results thus suggest that H4K16ac plays a dual role in myeloid cells as it not only regulates differentiation and apoptosis, but it also exhibits a non-canonical structural role in poising chromatin for cleavage at an early stage of neutrophil cell death

Famílies botàniques de plantes medicinals

Facultat de Farmàcia, Universitat de Barcelona. Ensenyament: Grau de Farmàcia, Assignatura: Botànica Farmacèutica, Curs: 2013-2014, Coordinadors: Joan Simon, Cèsar Blanché i Maria Bosch.Els materials que aquí es presenten són els recull de 175 treballs d’una família botànica d’interès medicinal realitzats de manera individual. Els treballs han estat realitzat per la totalitat dels estudiants dels grups M-2 i M-3 de l’assignatura Botànica Farmacèutica durant els mesos d’abril i maig del curs 2013-14. Tots els treballs s’han dut a terme a través de la plataforma de GoogleDocs i han estat tutoritzats pel professor de l’assignatura i revisats i finalment co-avaluats entre els propis estudiants. L’objectiu principal de l’activitat ha estat fomentar l’aprenentatge autònom i col·laboratiu en Botànica farmacèutica

Examining drinking consequences and reasons for drinking in a bilingual college sample

College drinking behavior is a national public health concern. However, little research has been conducted to test the psychometric validity and reliability of alcohol use measures among Spanish-speaking Hispanic college students. Adopting a translation-back-translation approach, the Rutgers Alcohol Problem Index (RAPI) was translated into Spanish and the Razones del Consumo de Alcohol (RCA), a newly created measure of one’s reasons for drinking, was developed in Spanish. Both measures were administered to 155 Spanish-speaking students at a university in the Southwestern United States. All translated measures demonstrated adequate internal consistency reliability. Support for the construct validity of the translated RAPI measure was demonstrated as gender and RCA scores were predictive of RAPI scores in their expected directions [R2 = .438, F(2, 138) = 53.36, p = .000]. Acculturation was not significantly associated with RAPI scores nor did acculturation interact with RCA scores to enhance the predictability of RAPI scores. Finally, an exploratory factor analysis was performed on the RCA revealing a one-factor solution as the most adequate description of the RCA data. Knowledge of reasons for drinking as assessed by the RCA seems useful in predicting drinkingrelated consequences among Hispanic college students

Hydrological and erosional impact and farmer's perception on catch crops and weeds in citrus organic farming in Canyoles river watershed, Eastern Spain

[EN] It is needed to find the proper management from a biophysical point of view to promote sustainable agriculture. However, it is also necessary that farmers accept new strategies that propose cultural and technical shifts. A survey of the fannerg perception, and an assessment of the biophysical impact of catch crops (CC) and weeds (W) on soil organic matter, bulk density, infiltration capacity, runoff initiation, runoff discharge and soil detachment at the pedon scale were carried out. The field measurements in the Alcoleja experimental station demonstrated that organic matter and bulk density after 10 years of Vicla saliva L and Avena saliva L catch crops and weeds managed plots are similar. Both CC and W plots enhanced high infiltration rates under single ring ponding conditions, the runoff discharge was delayed and decreased; and soil erosion rates were lower in comparison to soil erosion rates measured in chemically managed farms. Soil quality was high for both management strategies and soil erosion rates much sustainable due to the live mulch that catch crops and weeds developed. However, an assessment of the farmed perception in the Canyoles river watershed citrus production area in Eastern Spain demonstrated that the farmer's community did not accept the use of catch crops or weeds. The survey proved that the farmers would accept the use of CC and W if subsidies were paid. The farmers claimed for the payment of the seeds and sowing expenses plus a 57 (sic) ha(-1) for the CC and 75 (sic) ha(-1) for Won average. The farmers considered the use of CC and W as benefit for the society, but not for them.This paper is part of the results of research projects GL2008-02879/BTE, LEDDRA 243857 and RECARE-FP7 (ENV.2013.6.2-4, http://recare-project.eu). We thank the editors and reviewers for their improvements to and careful review of the paper. The second coauthor, J. Rodrigo-Comino, was issued a grant to complete this study and some other about vineyards under the framework of a short-term scientific mission (COST-STSM-ECOST-STSM-ES1306-010217-081877).Cerda, A.; Rodrigo-Comino, J.; Giménez Morera, A.; Keesstra, SD. (2018). Hydrological and erosional impact and farmer's perception on catch crops and weeds in citrus organic farming in Canyoles river watershed, Eastern Spain. Agriculture Ecosystems & Environment. 258:49-58. https://doi.org/10.1016/j.agee.2018.02.015S495825

VNIR–NIR hyperspectral imaging fusion targeting intraoperative brain cancer detection

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REPORTE CORTO/SHORT REPORT - CLONING, EXPRESSION AND CHARACTERIZATION OF THE P64k OUTER MEMBRANE PROTEIN FROM N. meningitidis

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